Turning off a Gene in Potatoes :Potato Chips with Less Carcinogens

Turning off a Gene in Potatoes :Potato Chips with Less Carcinogens

In a groundbreaking stride for food safety and snack lovers everywhere, scientists have made a leap forward in the battle against carcinogens found in one of our favorite treats: potato chips. By ‘flicking the switch’ on a gene responsible for the production of acrylamide, a known carcinogen, in cold-stored potatoes, they’ve paved the way for healthier fried foods across the globe.

“This discovery represents a significant advancement in our understanding of potato development and its implications for food quality and health,” stated Jiming Jiang, a Research Foundation Professor at Michigan State University (MSU). His work, alongside colleague David Douches, could revolutionize the way we store and consume potatoes, particularly in their most beloved form: the crispy, golden chip.

The US potato industry is a robust market, generating $240 million annually. To meet the year-round demand, potatoes are often stored in cold environments, which unfortunately triggers a natural process in the tubers that converts starches to sugars. This process, known as cold-induced sweetening (CIS), not only darkens the potato when cooked but also increases the levels of acrylamide, a substance with carcinogenic properties.

Solar Roasted Garlic Potatoes” by EBKauai is licensed under CC BY 2.0

The MSU scientists, Jiang and Douches, have identified the gene that regulates this temperature-driven sugar conversion, known as the potato vacuolar invertase gene, or VInv. By inhibiting this gene, potatoes can be stored in cold conditions without the risk of acrylamide formation during cooking. This not only benefits consumer health but also has the potential to save time and money for producers, as the need for interventions to reduce sugars in cold-stored tubers is eliminated.

“We’ve identified the specific gene responsible for CIS and, more importantly, we’ve uncovered the regulatory element that switches it on under cold temperatures,” explained Jiang. The implications of this research are vast, promising a future where potatoes can resist the sweetening process naturally, without the need for costly and flavor-altering techniques currently used to reduce sugar content.

The team at MSU is not just stopping at the laboratory doors. They are actively working on breeding techniques to produce these ‘healthier’ potatoes. “All our facilities are on campus so the research work can be done efficiently,” said Douches, who leads MSU’s potato breeding and genetics program. Their collaboration has set the stage for targeted genetic modification to create cold-resistant potato varieties.

The study, published in the journal The Plant Cell, is not a mere academic exercise. It has real-world implications for the $250 billion global savory snack market and sets a new standard for global food health standards. With nearly 300 million Americans projected to enjoy potato chips this year, the impact of this research is not to be underestimated.

The potential of this discovery extends beyond just potato chips. Acrylamide is a concern in various starchy foods processed at high temperatures, and the breakthrough at MSU could have broader implications for food safety in general.

“Our next steps involve using this knowledge to create CIS-resistant potato lines through gene editing or other breeding techniques in Dr. Douches’ greenhouses,” Jiang added, indicating that the journey from lab to greenhouse to chip bag is well underway.

The work of Jiang and Douches at MSU represents more than just a scientific curiosity; it is a step towards a future where our favorite snacks are not only tastier but also safer. As Jiang puts it, this advancement “has the potential to affect every single bag of potato chips around the world,” making it a pivotal moment for both the potato industry and consumers alike.

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